Matching of digitised brain atlas to magnetic resonance images |
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Authors: | C Sorlié O Bertrand B Yvert J -C Froment J Pernier |
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Institution: | (1) INSERM U280, Brain Signals and Processes Laboratory, 151, cours Albert Thomas, 69424 Lyon cedex 03, France;(2) MRI Laboratory, Neurological Hospital, Lyon, France |
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Abstract: | A method has been developed to match a standard digitised brain atlas onto MR images for identification of cerebral structures
in anatomical images. This method uses, first, a three-dimensional crude registration based on the proportional system of
Talairach. Then, a two-dimensional refined registration is performed using a deformation function based on a set of homologous
landmarks on both images (MR and atlas). Displacements vectors are computed between each corresponding landmark. These vectors
are interpolated by thin-plate splines, generating an unwarping function defined on the whole image. This function can then
be applied on any structure of the atlas. An evaluation of the matching procedure has been performed. First, the influence
of the choice of the landmarks has been evaluated for the fine registration method. The latter has been then compared to the
crude registration method considered as a classical reference method. These results show the advantages of the fine registration
approach. |
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Keywords: | Digitised brain atlas MRI Brain anatomy Image matching |
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