右美托咪定对高血压患者喉罩置入期间麻醉深度的影响

目的观察预输注不同剂量右美托咪定对原发性高血压患者喉罩置入期间麻醉深度的影响。方法选择患有原发性高血压行普外科和妇科择期腹腔镜手术中喉罩通气患者60例，ASAI-Ⅱ级，随机分为三组（n=20）。麻醉诱导前后分别记录不同剂量DEX（B组和C组）或生理盐水（A组）注射前（Tn）、麻醉诱导前（T1）、喉罩置入前（T2）、喉罩置入后即刻（T3）、喉罩置入后3min（T4）、5min（T5）时相的MBP、HR、BIS。结果与A组比较，B组和C组均可降低BIS，保持喉罩置入期间血流动力学的平稳。但C组在喉罩置入前后的显著心率过缓发生率高于B组。结论诱导前15min预注DEX0．2μg／kg可以安全有效地控制高血压患者喉罩置入期间的麻醉深度。

Effects of dexmedetomidine on depth of anesthesia in hypertensive patients during inserting laryngeal mask airway

Objective To investigate the effects of pre-injection of different dosage dexmedetomidine(DEX) on depth of anesthe sia in primary hypertensive patients during inserting laryngeal mask airway(LMA).Methods Sixty ASA Ⅰ or Ⅱ primary hypertensive patients who were scheduled for elective general surgery or gynecological laparoscopic operation were randomized into three groups with 20 cases each.MAP,HR and BIS were detected before injecting different dosage DEX or normal saline(T0),before induction(T1),before inserting LMA(T2),after inserting LMA immediately(T3),at 3 min(T4) and 5 min(T5) after inserting LMA.Results Compared with the A group,BIS was decreased in group B and C after injecting DEX.DEX could keep the hemodynamics stable.The rate of significant bradycardia in group C was higher than group B.Conclusion It is safe and available to control depth of anesthesia in hypertensive patients during inserting LMA by injection of 0.2 μg/kg DEX in 15 min before induction.