肝移植科围手术期患者抗菌药物使用分析

目的分析肝移植科对围手术期抗菌药物使用情况,以提高临床合理使用抗菌药物的水平。方法随机抽取2005年1月-2006年12月肝移植科出院的206例病历,采用世界卫生组织推荐限定日剂量(DDD)及药物利用指数(DUI)为指标,对抗菌药物的合理使用进行回顾性分析。结果肝移植科206例围手术期患者抗菌药物使用率达100.0%,涉及6大类、13种抗菌药物,其中单用137例,占66.5%;二联64例,占31.1%;三联5例,占2.4%;统计的13种抗菌药物中有12种DUI≤1。结论肝移植科围手术期抗菌药物使用基本合理。

Anti-bacterial Drugs Applying in Liver Transplanting Patients During Perioperative Period:A Survey and Analysis

OBJECTIVE To find out the situation of the application of anti-bacterial drugs in liver transplantation perioperative patients and to improve the quality of their usage.METHODS According to the criteria of DDD and DUI recommended by WHO,making a random sampling survey of the application of anti-bacterials in 206 liver transplantation perioperative patients who discharged hospital during Jan-Dec 2006,and then to analyze the rationality of their application.RESULTS Among the 206 patients,100.0% patients had received anti-bacterial drugs involving 13 kinds,137 patients in them used one,31.1% used two and 2.4% used three,and there were twelve in thirteen kinds of drugs whose DUI was no more than one.CONCLUSIONS The survey has proved that the liver transplantation perioperative patients have received rational therapy.