| Abstract: | ![]()
To evaluate the reliability and validity of the Patient Health Questionnaire‐9 (PHQ‐9) in patients with acne. Three hundred acne patients were enrolled from January 2019 to December 2019. PHQ‐9 and Hamilton Depression Scale(HAMD) survey was conducted to evaluate their depression status. Cronbach's α coefficient and test‐retest reliability after 1 week were used to analyze the reliability of PHQ‐9. Factor analysis, Spearman correlation analysis, receiver operating characteristic curve (ROC curve) were used for validity analysis of the PHQ‐9.The screening validity was analyzed in different subgroups. Two hundred fifty‐eight patients with acne completed the questionnaire. Forty‐seven were diagnosed with depressive disorder. The best cut‐off point for the PHQ‐9 score is 9 points, with a sensitivity of 95.7%,a specificity of 88.6% and the area under the ROC curve(AUC) of 0.973.In validity analysis, the correlation coefficient between the total score of PHQ‐9 and HAMD was 0.766,the kappa value was 0.530.Factor analysis revealed two common factors (cognitive‐affective factor and somatic symptom factor),which explained 65.52% of the total variances. In reliability analysis, the Cronbach's α coefficient of the PHQ‐9 was 0.851,the test‐retest reliability value was 0.824.The time to complete the PHQ‐9 was significantly less than the time to complete HAMD (P < .001).The PHQ‐9 shows good reliability and validity for the diagnosis of depression in patients with acne, and can be used for preliminary screening of depression. |
