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Liver Recurrence of a Subcutaneous Temporal Hemangiopericytoma: The Index Case
Authors:Stéphane Zalinski  Claire Goumard  Olivier Scatton  Benoit Terris  Francoise Plantier  Nicolas Dupin  Olivier Soubrane
Affiliation:1. Department of Hepatobiliary Surgery and Liver Transplantation, H?pital Cochin, Assistance Publique-H?pitaux de Paris, 27 rue du Faubourg Saint Jacques, 75014, Paris, France
4. University Paris Descartes, Paris, France
2. Department of Pathology, H?pital Cochin, Assistance Publique-H?pitaux de Paris, 27 rue du Faubourg Saint Jacques, 75014, Paris, France
3. Department of Dermatology, H?pital Cochin, Assistance Publique-H?pitaux de Paris, 27 rue du Faubourg Saint Jacques, 75014, Paris, France
Abstract:Introduction  Hemangiopericytoma is an uncommon soft tissue vascular neoplasm. Intraperitoneal hemangiopericytomas such as primary or secondary liver location have been exceptionally described. Its natural history is mostly benign, but recurrences may occur and determining if these late-discovered tumors are distant metastases or synchronous slow and silent-growing locations is sometimes challenging. The histopathological diagnosis and definition of hemangiopericytoma is based on its distinction with solitary fibrous tumors. Liver resection to treat liver hemangiopericytoma seems to be supported by various published experiences. Case presentation  We herein report the first case of liver metastases from a subcutaneous temporal hemangiopericytoma. The patient was treated by a liver resection. CD34 Immunostaining was negative, but strong expression of Bcl2 and CD99 was found in the neoplastic cells. After 1 year of follow-up, the patient is alive without recurrence. Conclusion  To date, published data, including the case herein reported, support the need for a prolonged follow-up and the role of liver resection to treat liver metastases of hemangiopericytomas. Complete resection of all gross disease appears to be the most significant prognostic factor.
Keywords:Subcutaneous hemangiopericytoma  Liver metastases  Hepatic resection
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