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致病性大肠杆菌和出血性大肠杆菌的研究进展
引用本文:王建阳. 致病性大肠杆菌和出血性大肠杆菌的研究进展[J]. 中国热带医学, 2004, 4(2): 292-293,294
作者姓名:王建阳
作者单位:河南省卫生防疫站,河南,郑州,450003
摘    要:
致病性大肠杆菌(EPEC)是导致婴幼儿腹泻的主要病原菌,特别在发展中国家。近期研究表明,EPEC病原与宿主细胞的作用可视为三个阶段。第一阶段,局限性的粘附在上皮细胞;第二阶段,产生分泌蛋白:第三个阶段,紧密粘附和受体蛋白的作用。一些出血性大肠杆菌侵袭人的肠上皮细胞也靠粘附和损伤作用。

关 键 词:致病性大肠杆菌 出血性大肠杆菌 婴幼儿 腹泻 致病机理
文章编号:1009-9727(2004)02-292-03

Research progress in enteropathogenic Escherichia coli and enterohemorrhagic Escherichia coli
WANG Jian yang. Research progress in enteropathogenic Escherichia coli and enterohemorrhagic Escherichia coli[J]. China Tropical Medicine, 2004, 4(2): 292-293,294
Authors:WANG Jian yang
Abstract:
EPEC is a major cause of infantile diarrhoea,particularly in developing countries Recent research showed,interactions between EPEC and host cells entail several distinct steps and have classically been viewed as a three stage process In the first stage,localized EPEC adherence to epithelial cells,the second stage of EPEC pathogenesis involves the production of bacterial proteins the third stage of EPEC infection is intimate adherence and the role of Tir Some EHEC attaches to cells in the human gut epithelium by "attaching/effacing"(A/E) lesions
Keywords:Enteropathogenic Escherichia coli  Enterohemorrhagic Eshcherichia coli  Research progress
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