The dynamics of multiple sclerosis |
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Authors: | W. I. McDonald |
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Affiliation: | (1) NMR Research Group, Institute of Neurology, WClN 3BG Queen Square, London, UK |
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Abstract: | The history of our understanding of the pathogenesis and pathophysiology of multiple sclerosis are reviewed in the context of Charcot's contribution. The implications for treatment of the new knowledge gained from studies during life of pathology and pathogenesis (by MRI) and pathophysiology (by evoked potentials) are reviewed.Based on the Charcot lecture given to the International Federation of Multiple Sclerosis Societies, Amsterdam, October 1991 |
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Keywords: | Multiple sclerosis Inflammation Demyelination Axonal degeneration Gliosis |
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