Increased sexual motivation in female rats treated with Humulus lupulus L. extract期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Increased sexual motivation in female rats treated with Humulus lupulus L. extract

Authors:	Di Viesti Vittoria Carnevale Gianluca Zavatti Manuela Benelli Augusta Zanoli Paola

Institution:	^a Department of Biomedical Sciences, Section of Pharmacology, University of Modena and Reggio Emilia, Via Campi 287, 41100 Modena, Italy ^b Department of Anatomy and Histology, University of Modena and Reggio Emilia, 41100 Modena, Italy

Abstract:	Aim of the study To evaluate the influence of Humulus lupulus extract on sexual behavior in female rats. Materials and methods Ovariectomized rats hormonally primed with estradiol benzoate (1.5 μg/rat) and progesterone (500 μg/rat) were acutely treated by oral gavage with Humulus lupulus extract dosed at 5, 10 and 25 mg/kg and then tested for partner preference and sexual receptivity. Results The administration of Humulus lupulus extract at the highest dose significantly increased the preference for the stimulus male during the partner preference test and the number of proceptive behaviors during the receptivity test, without affecting the lordosis response. Conclusions Humulus lupulus extract increased sexual motivation in hormone-primed female rats.

Keywords:	Humulus lupulus Female rat Sexual motivation
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