四川省食管癌早诊早治效果评价

[目的]评价食管癌高发区早诊早治项目筛查人群食管癌及癌前病变的患病情况。[方法]在四川省食管癌高发地区,采取整群随机抽样的方法选择至少一个乡或村作为筛查对象,对40~69岁人群采取内镜下碘染色及指示性活检技术进行筛查,并行病理学诊断。[结果]全省合计筛查11021人,筛查率100.19%;重度异形增生/原位癌及以上病人检出168例,检出率为1.53%;其中食管癌61例,检出率为0.55%。全省早诊率67.86%;治疗率67.26%。[结论]在食管癌高发区人群中存在着一定数量的无明显临床症状的癌前病变及早期食管癌患者,对该部分高危人群进行食管癌普查并进行癌症综合知识宣传,提高其防癌意识,是提高早期食管癌检出率,做好食管癌二级预防工作的关键。

Evaluation on Effect of Early Diagnosis and Treatment for Esophageal Cancer in Sichuan Province

[Purpose] To investigate the prevalence of esophageal and precancerous lesions in high risk areas undergoing early diagnosis and treatment project. [Methods] Residents at least in one township or village were selected as a screening object by random cluster sampling method in high risk areas. Endoscope iodine staining and index biopsy screening method was used for 40~69 years old people, also pathological examination. [Results] A total of 11 021 persons were screened with screening rate 100.19%. Severe esophageal heterosexual hyperplasia/carcinoma in situ and severe lesions was found in 168 cases, with detection rate 1.53%, and esophageal cancer 61 cases with detection rate 0.55%. In the province, early diagnosis rate was 67.86%; treatment rate was 67.26%. [Conclusion] Among population in esophageal high incidence areas, a certain number of early esophageal cancer and precancerous lesions with no obvious symptoms is exist. Screening for esophageal cancer and cancer prevention education to high risk population are the key of secondary prevention.