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慢性阻塞性肺疾病与小细胞肺癌危险性关系探讨
引用本文:许瑞玉,戴元荣,颜孙舜,徐慧.慢性阻塞性肺疾病与小细胞肺癌危险性关系探讨[J].温州医学院学报,2012,42(3):250-252.
作者姓名:许瑞玉  戴元荣  颜孙舜  徐慧
作者单位:温州医学院附属第二医院呼吸内科,浙江温州,325027
摘    要:目的:分析慢性阻塞性肺疾病(COPD)与小细胞肺癌(SCLC)的危险性关系.方法:采用病例对照的方法,回顾性地分析SCLC发病的危险因素.结果:吸烟是COPD和SCLC的共同致病因素(均P< 0.05);具有COPD、肺气肿、支气管炎病史者发生SCLC的危险性明显增高(P<0.05);控制吸烟因素的影响,有COPD病史者发生SCLC的危险性仍明显增高(P<0.05).结论:COPD是SCLC的独立危险因素.

关 键 词:慢性阻塞性肺疾病  肺癌  小细胞性  吸烟

Relationship between chronic obstructive pulmonary disease and small cell lung cancer
XU Ruiyu , DAI Yuanrong , YAN Sunshun , XU Hui.Relationship between chronic obstructive pulmonary disease and small cell lung cancer[J].Journal of Wenzhou Medical College,2012,42(3):250-252.
Authors:XU Ruiyu  DAI Yuanrong  YAN Sunshun  XU Hui
Institution:.Department of Respiratory Medicine,the Second Affiliated Hospital of Wenzhou Medical College,Wenzhou,325027
Abstract:Objective: To analyze the relationship between chronic obstructive pulmonary disease(COPD)and the risk of small cell lung cancer(SCLC).Methods: Using a case-control method,the risk factors for SCLC were retrospectively analyzed.Results: Smoking was a causal factor of SCLC and COPD.COPD increased the risk of SCLC(P <0.05,adjusted OR value:3.160,95% CI:0.633-15.774).Conclusion: COPD is an independent risk factor for SCLC.
Keywords:chronic obstructive pulmonary disease  small cell lung cancer  smoking
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