| MircoRNA-26a与肿瘤 |
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| 引用本文： | 宋倩倩,徐克. MircoRNA-26a与肿瘤[J]. 中国肺癌杂志, 2017, 0(11): 769-774. DOI: 10.3779/j.issn.1009-3419.2017.11.08 |
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| 作者姓名： | 宋倩倩 徐克 |
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| 作者单位： | 300052 天津,天津医科大学总医院,天津市肺癌研究所,天津市肺癌转移和肿瘤微环境重点实验室 |
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| 基金项目： | This paper was supported by the grants from the National Natural Science Foundation of China(81372519)，the Specialized Research Fund for the Doctoral Program of Higher Education of China(20131202110005)，the Key Proj-ect of Tianjin Municipal Science and Technology Commission (No.14JCZDJC33800;No.10JCZDJC20800)(All to Ke XU).本文受国家自然科学基金(81372519)，教育部博士点基金(20131202110005)，天津市应用基础及前沿技术研究计划重点项目(14JCZDJC33800 |
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| 摘 要： | 微小RNA(microRNAs,miRNAs)是一类由20个-22个核苷酸组成的小片段非编码RNA,通过靶向结合基因mRNA的3'非翻译区(3'-UTR)调控其表达.许多研究报道miRNAs参与肿瘤的发生发展.MiR-26a在不同的肿瘤中发挥不同的作用,在肿瘤增殖、转移侵袭、血管形成、生物代谢及诊断预后中都有作用.本文就miR-26a与肿瘤关系的研究进展进行综述.
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| 关 键 词： | miR-26a 靶基因 肿瘤 |
MicroRNA-26a and Tumor |
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| Qianqian SONG,Ke XU. MicroRNA-26a and Tumor[J]. Chinese journal of lung cancer, 2017, 0(11): 769-774. DOI: 10.3779/j.issn.1009-3419.2017.11.08 |
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| Authors: | Qianqian SONG Ke XU |
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| Abstract: | MicroRNAs are a class of small noncoding RNAs (20-22 nucleotides). MicroRNAs regulate gene ex-pression by directly binding gene's 3'-UTR regions. Many studies reveal that miRNAs play roles in tumorigenesis. MiR-26a plays different roles in different types of cancer, and participates in tumor growth, invasion, metastasis, angiogenesis, metabo-lism, diagnosis and prognosis. This review summarizes the progress of miR-26a study in cancer. |
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| Keywords: | miR-26a Target genes Tumors |
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