|
|||||
|
|
Successful unrelated bone marrow transplantation in a child with chronic granulomatous disease complicated by pulmonary and cerebral granuloma formation |
|
| Authors: | Catharina Schuetz Manfred Hoenig Ansgar Schulz Min Ae Lee-Kirsch Joachim Roesler Wilhelm Friedrich Horst von Bernuth |
| Affiliation: | (1) Department of Pediatrics, University of Ulm, Eythstrasse 24, 89073 Ulm, Germany;(2) Department of Pediatrics, Technical University of Dresden, Dresden, Germany;(3) Laboratory of Human Genetics of Infectious Diseases, University of Paris René Descartes-INSERM U550, Necker Medical School, 75015 Paris, France |
| Abstract: | We report on a 6-year-old boy with chronic granulomatous disease (CGD) complicated by chronic inflammatory reactions with formation of large pulmonary granuloma as well as intracerebral lesions. Bone marrow transplantation (BMT) from an unrelated donor led to stable reconstitution, to rapid resolution of pulmonary granuloma, and to rapid resolution of intracerebral lesions. |
| Keywords: | Chronic granulomatous disease Granuloma formation Cerebral lesions Bone marrow transplantation |
| 本文献已被 PubMed SpringerLink 等数据库收录！ | |