心理干预对乳腺癌化疗患者生活质量的影响

目的探讨综合心理治疗对乳腺癌化疗患者焦虑抑郁及胃肠反应的影响。方法将164例乳腺癌化疗患者随机分为对照组（82例）和心理干预组（82例）。两组均采用常规化疗方案,心理干预组同时配合综合心理治疗3周。采用症状自评表评定患者精神症状。治疗前后采用焦虑自评量表（SAS）和抑郁自评量表（SDS）进行检测。组间采用t检验。结果患者症状自评量表各因子与正常人常模比较,躯体化、抑郁、焦虑、恐怖因子评分明显升高（P〈0.01）。心理干预组第5周SDS及SAS评分均明显低于对照组,胃肠道反应亦减轻。结论乳腺癌患者存在明显的心理障碍,综合心理治疗科明显降低乳腺癌化疗患者抑郁、焦虑程度及胃肠道反应。

Effect of psychotherapy on depression, anxiety and gastrointestinal reactions in patients with breast cancer undergoing chemotherapy

Objective To investigate the effect of comprehensive psychotherapy on depression,anxiety and gastrointestinal reactions in patients with breast cancer.Methods 186 cases with breast cancer were randomly divided into psychotherapy group and control group which were both treated with routine chemotherapy.Those in the control group concomitantly received comprehensive psychocherapy for 4 weeks.Their characters of Symptom Checklist 90（SCL-90） were measured,while those of self-rating Anxiety Scale（SAS） and Self-rating Depression Scale（SDS） were also measured before and after treatment.Results The scores of SCL-90 in patients with breast cancer were increased compared with Chinese norm in somatization,depression,anxiety,phobic anxiety（P0.01）.From the 5th week,the scores of SDS and SAS in the psychotherapy group were significantly lower than those in the control group（p0.01）,as well as the gastrointestinal reactions.Conclusion Psychotherapy can obviously decrease the severity of depressive and anxious emotions and the gastrointestinal reactions.