Cortical microinfarcts on 7T MRI in patients with spontaneous intracerebral hemorrhage |
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| Authors: | Susanne J van Veluw Wilmar M T Jolink Jeroen Hendrikse Mirjam I Geerlings Peter R Luijten Geert Jan Biessels Catharina J M Klijn |
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| Affiliation: | 1Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands;2Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands;3Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands |
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| Abstract: | ![]()
In patients with spontaneous intracerebral hemorrhage (ICH) coexisting abnormalities on brain imaging can provide clues on the etiology of the underlying small vessel disease. We examined cortical cerebral microinfarcts as a novel marker of coexistent vascular damage in ICH. Twelve patients with spontaneous ICH and 15 controls underwent 7Tesla magnetic resonance imaging (MRI). Microinfarcts were present in 9 of 12 patients with spontaneous ICH, and in 5 of 15 controls. This explorative study shows, for the first time, that microinfarcts appear to be a very common vascular comorbidity in spontaneous ICH. Future larger studies should further assess the etiological significance of these lesions. |
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| Keywords: | high-field MRI microbleeds microinfarcts small vessel disease spontaneous intracerebral hemorrhage |
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