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| CSH、SOD和ATP-MgCl_2对静脉皮瓣成活的影响 | |
| 引用本文： | 修志夫,陈宗基. CSH、SOD和ATP-MgCl_2对静脉皮瓣成活的影响[J]. 中华实验外科杂志, 1995, 0(1) |
| 作者姓名： | 修志夫 陈宗基 |
| 作者单位： | 中国医学科学院整形外科医院，中国医学科学院整形外科医院 100041 北京，100041 北京 |
| 摘 要： | 在兔胸腹部以胸腹壁静脉为轴形成4cm×6cm的静脉皮瓣。经静脉注射GSH,SOD,ATP-Mg-Cl_2,分别观察这三种药物对静脉皮瓣成活的影响。结果表明这三种药物使用后静脉皮瓣成活面积百分率分别为:GSH组86.56％、SOD组85.52％、ATP-mgcl2组76.25％,均显著高于对照组68.75％。文中对这三种药物提高静脉皮瓣成活面积的机制进行了探讨。 |
| 关 键 词： | 静脉皮瓣成活 ATP-MgCl_2 GSH SOD |
The effect of GSH, SOD and ATP-MgCl_2 on venous flap survival |
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| Xiu Zhifu and ChenZongji. Plastic Surgery Hospiatl of Chinese A-cademy of Medical Sciences,Beijing .. The effect of GSH, SOD and ATP-MgCl_2 on venous flap survival[J]. Chinese Journal of Experimental Surgery, 1995, 0(1) | |
| Authors: | Xiu Zhifu ChenZongji. Plastic Surgery Hospiatl of Chinese A-cademy of Medical Sciences Beijing . |
| Affiliation: | Xiu Zhifu and ChenZongji. Plastic Surgery Hospiatl of Chinese A-cademy of Medical Sciences,Beijing 100041. |
| Abstract: | Oxygen radicals and energy supply are important factors affecting flap survival. To investigate the effect of free radical scavengers (GSH, SOD) and ATP-MgCl2 on venous flap survival, an experimental study was designed. Four 4X6 cm venous flaps along the axis of the thoracoepigastric veins in each rabbit were elevated. GSH, SOD and ATP-MgCl2 were administered intravenously in the postoperative period, and survival sizes of venous flaps were measured at 2 weeks. GSH, SOD and ATP-MgCl2 showed mean flap survival rates of 76% to 87% each of which was significantly improved over saline control (68.75%, P < 0. 01) The mechanisms are discussed. |
| Keywords: | Venous flap survival GSH SOD ATP-MgCl_2 |
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