龋病发生中的宿主因素与时间因素龋病学研究百年回顾与展望之四

本文回顾了20世纪和21世纪初对龋病发生中的宿主因素、时间因素研究的主要内容。宿主因素中包括全身和局部因素，前者为全身性疾病对机体龋敏感性或抗龋性的影响以及遗传因子对龋病发生的作用，后者主要回顾了牙齿本身、唾液、口腔卫生与龋病发病的关系。关于时间因素过去研究的内容不多，本文就已知和可能出现的某些因素作一些分析。

Host factors and time factors in cariogenesis A review of caries research in last century

The host factors and time factors contributed in eariogenesis are reviewed concisely in this paper. Systemic diseases and genetic factors which may affect the production of the disease are described. Works on local factors as tooth itself, saliva and oral hygienic condition may associated with caries production are discussed. The time factor accounted in the pathogenic process is also decribed.