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Detection of Norovirus Variant GII.4 Hong Kong in Asia and Europe, 2017−2019
Authors:Martin Chi-Wai Chan,Sunando Roy,Joseph Bonifacio,Lin-Yao Zhang,Preeti Chhabra,Jenny C.M. Chan,Cristina Celma,Mary Ann Igoy,Sin-Leung Lau,Kirran N. Mohammad,Jan Vinj  ,Harry Vennema,Judith Breuer,Marion Koopmans,Miranda de Graaf,for NOROPATROL
Abstract:We report a new norovirus GII.4 variant, GII.4 Hong Kong, with low-level circulation in 4 Eurasia countries since mid-2017. Amino acid substitutions in key residues on the virus capsid associated with the emergence of pandemic noroviruses suggest that GII.4 Hong Kong has the potential to become the next pandemic variant.
Keywords:norovirus   viruses   norovirus GII.4   new variant   surveillance   gastroenteritis   enteric infections   communicable diseases   Eurasia   Hong Kong   the Philippines   the Netherlands   United Kingdom
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