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Novel 6-Month Treatment for Drug-Resistant Tuberculosis,United States |
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| Authors: | Connie A. Haley Patricia Macias Supriya Jasuja Betsy A. Jones Marie-Claire Rowlinson Roshni Jaimon Pennelyn Onderko Elaine Darnall Maria E. Gomez Charles Peloquin David Ashkin Neela D. Goswami |
| Abstract: | The US Food and Drug Administration approved a 6-month regimen of pretomanid, bedaquiline, and linezolid for extensively drug-resistant or multidrug-intolerant tuberculosis after a trial in South Africa demonstrated 90% effectiveness 6 months posttreatment. We report on a patient who completed the regimen using a lower linezolid dose. |
| Keywords: | tuberculosis and other mycobacteria antimicrobial resistance drug monitoring bedaquiline pretomanid linezolid BPaL Nix-TB United States bacteria |