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| 帕金森病相关疼痛 | |
| 引用本文： | 张飘,王丽娟,张玉虎. 帕金森病相关疼痛[J]. 临床神经病学杂志, 2020, 33(3): 229-232 |
| 作者姓名： | 张飘 王丽娟 张玉虎 |
| 作者单位： | 510515 广州,南方医科大学第二临床医学院;广东省人民医院(广东省医学科学院)神经内科,广东省神经科学研究所 |
| 基金项目： | 广州市民生科技攻关计划资助项目;国家重点研发计划;国家自然科学基金;广东省自然科学基金重点项目;广东省医学科研基金 |
| 摘 要： | 疼痛是帕金森病最常见且最棘手的非运动症状,其患病率高达40%以上。PD的疼痛可分为许多不同的亚型,包括肌肉骨骼、肌张力障碍、根性/神经性痛、中枢性疼痛以及静坐不能等。PD相关疼痛尚无统一的评估标准,难以开展个性化治疗,但左旋多巴能改善多数PD相关疼痛患者。其发病可能与CNS的外侧和内侧感觉系统以及外周神经病变有关,但具体机制尚未明确。 |
| 关 键 词： | 帕金森病 发病机制 疼痛评估 治疗 |
Parkinson's disease related pain |
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| ZHANG Piao,WANG Li-juan,ZHANG Yu-hu. Parkinson's disease related pain[J]. Journal of Clinical Neurology, 2020, 33(3): 229-232 | |
| Authors: | ZHANG Piao WANG Li-juan ZHANG Yu-hu |
| Affiliation: | (the Second School of Clinical Medicine,Southern Medical University,Guangzhou 510515,China) |
| Abstract: | Pain is the most common and tricky non-motor symptom of Parkinson's disease,with a prevalence of over 40%.PD related pain may be divided many different subtypes,including musculoskeletal,dystonic,radicular neuropathic,central pain and akathitic discomfort.There is no uniform assessment standard for PD related pain,it is difficult to develop personalized treatment,but levodopa can improve most cases.Its pathogenesis may be related to the lateral and medial sensory systems of the central nervous system and peripheral neuropathy,but the specific mechanism has not yet been clarified. |
| Keywords: | Parkinson's disease pathogenesis pain assessment treatment |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |