422例非囊性纤维化支气管扩张症临床特点分析

目的了解支气管扩张症的临床特点及不同类型支气管扩张症临床特点的差异。方法回顾性分析2014年10月至2016年10月期间在四川省人民医院(东院)呼吸内科住院治疗的422例非囊性纤维化支气管扩张症患者的临床资料,并比较不同影像学类型的患者的临床特点差异。结果422例患者中男性201例(47.6%),女性221例(52.4%),中位年龄60.87±12.66岁,中位患病时间16.63±15.81年,不同影像学类型的支气管扩张症分类:囊状型62例(14.7%),柱状型211例(50%),囊柱状型149例(35.3%)。分析三组数据:柱状型支气管扩张症患病时间最短,平均住院时间最短,咳痰、出现肺部湿啰音及哮鸣音较少,血清CRP水平、外周血中心粒细胞计数水平、动脉血PaCO 2水平较低,较少感染铜绿假单胞菌及较少并发慢性肺源性心脏病(P<0.0167)。结论不同影像类型的支气管扩张症,以柱状型最为常见,其病情较囊状型及囊柱状轻,根据影像学类型,可对支气管扩张症患者进行分类管理。

Clinical feature analysis of 422 cases with non-cystic fibrosis bronchiectasis

Objective To understand the clinical features of non-cystic fibrosis bronchiectasis and to compare its clinical features of different types.Methods The clinical data of 422 non-cystic fibrosis bronchiectasis patients hospitalized in the East Hospital District of the People's Hospital of Sichuan from October 2014 to October 2016 were retrospectively analyzed, then its clinical features were compared with different imaging types with chest high resolution CT. Results With a total 422 patients, 201 (47.6%) were male and 221 (52.4%) were female. The middle age was 60.87±12.66 years, and the middle time of illness was 16.63±15.81 years. The types of bronchiectasis were cystic in 14.7%, cylidrial in 50%, and varicose in 35.3%. Cylindrical bronchiectasis had the shortest sick time and hospital stay, rare sputum, moist sounds and wheezing sounds, the lowest level of serum neutrophil, CRP and arterial blood PaCO 2, and the least infected Pseudomonas aeruginosa and combined with chronic pulmonary heart disease ( P <0.05). Conclusion Different types of bronchiectasis clinical features are different, and cylidrial is the most common type, with less severe situation than the other two types. It is better to understand their clinical features for clinical diagnose and treatment.