女性被动吸烟与冠心病

Women's passive smoking and coronary heart disease

Thirty-four women CHD cases (22 cases diagnosed by coronary arteriography and 12 myocardial infarction) and 68 of non-CHD controls (34 hospital based and 34 population based), matched on age (within five years), race, residence, occupation (and case is to control as 1:2), were interviewed regarding the smoking habits of themselves and their husbands. The odds ratio (i.e. OR) of non-smoking women CHD associated with having a smoking husband are 3.00-3.52, OR 95% CI do not include 1. Significant dose-response relationships between OR of women's CHD and their husband's cigarette consumption, duration of passive smoking and cumulative quantity of passive smoking were found in the study. The logistic regression model analysis with other CHD risk factors showed that the relationship with CHD and passive smoking still existed. It was found that the metabolism of HDL-cholesterol and apolipoproteins with passive smokers was abnormal.