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微乳对槲皮素增溶作用的实验研究
引用本文:马玉坤,冯杨,孔蓓蓓,邹满. 微乳对槲皮素增溶作用的实验研究[J]. 齐鲁药事, 2004, 23(3): 46-48
作者姓名:马玉坤  冯杨  孔蓓蓓  邹满
作者单位:1. 济南第二人民医院,济南,250000
2. 山东大学药学院,济南,250012
3. 山东体育学院图书馆,济南,250012
摘    要:目的 研究O/W型微乳对槲皮素的增溶作用。方法 以三角相图法制备了吐温 80 -乙醇 -花生油 -水的微乳体系,用比色法测定了在微乳、水和吐温 80 -乙醇 -水体系中槲皮素的溶解度,并考察了槲皮素O/W型微乳的初步稳定性。结果槲皮素在微乳中的溶解度为水中的 5 0倍以上。结论 所制备的微乳对槲皮素有明显的增溶作用。

关 键 词:微乳  三角相图  表面活性剂  槲皮素
文章编号:1672-7738(2004)03-0046-03

Study on the enhancing effect of microemulsion on solubility of Quercetin
Ma Yu-kun,Feng Yang,Kong Bei-bei,Zou Man. Study on the enhancing effect of microemulsion on solubility of Quercetin[J]. qilu pharmaceutical affairs, 2004, 23(3): 46-48
Authors:Ma Yu-kun  Feng Yang  Kong Bei-bei  Zou Man
Affiliation:Ma Yu-kun,Feng Yang,Kong Bei-bei1,Zou Man2
Abstract:Objective To study the enhancing effect of O/W microemulsion on the solubility of Quercetin. Methods Microemulsion system containing tween 80-alcohol-peanut oil-water was prepared based on the triangle phasdiagram diagram, and solubility of Quercetin in microemulsion, water and tween 80-alcohol-water was analysed by the way of UV. The stability of microemulsion was preliminarily examined. Results Solubility of Quercetin in microemulsion was 50 times more than that in water. Conclusion The prepared microemulsion had significantly enhancing effect on the solubility of Quercetin.
Keywords:microemulsion  triangle phasdiagram diagram  surfactant  Quercetin
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