丁苯酞软胶囊治疗基底动脉尖综合征的疗效观察

目的 观察丁苯酞软胶囊治疗轻、中度基底动脉尖综合征的临床疗效.方法 将60例轻、中度基底尖动脉综合征患者随机分为治疗组和对照组,每组各30例.对照组予以常规治疗,治疗组在常规治疗基础上加用丁基苯酞软胶囊口服,疗程为14d.采用NIHSS评分与BI评分评价治疗前,治疗后第7天和第14天两组的神经功能与日常生活能力.结果 治疗后两组的NIHSS评分显著降低,BI评分显著增高(P＜0.05).治疗组在治疗后第7天和第14天的NIHSS评分明显低于治疗前及对照组,差异均具有统计学意义(P＜0.05)；在治疗后第7天和第14天的BI评分则明显高于治疗前及对照组,差异均具有统计学意义(P＜0.05).结论 丁苯酞软胶囊治疗轻度中度基底动脉尖综合征具有较好的临床疗效.

Efficacy of butylphthalide soft capsules in the treatment of the top of the basilar syndrome

Objective To study the efficacy of butylphthalide soft capsules in the treatment of mild and moderate top of the basilar syndrome.Methods Sixty patients with mild and moderate top of the basilar syndrome were randomly divided into treatment and control groups (30 cases each). The patients in the control group were given conventional treatment and those in the treatment group were administered with butylphthalide soft capsules based on the conventional treatment. The course of the treatment was 14 days. Nerve function and activities daily living were evaluated by NIHSS and BI scores before treatment and the 7th and 14th days after treatment.Results NIHSS scores were reduced and BI scores were increased significantly in the two groups after treatment (P<0.05). The NIHSS scores in the treatment group on the 7th and 14th days after treatment were significantly lower than those before treatment and the control group (P<0.05). The BI scores in the treatment group were significantly higher than those before treatment and the control group on the 7th and 14th days after treatment (P<0.05).Conclusions Butylphthalide soft capsules is effective in the treatment of mild and moderate top of the basilar syndrome.