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300例高龄冠心病患者心率变异性分析
引用本文:周冬翠,裴志勇,毕磊. 300例高龄冠心病患者心率变异性分析[J]. 医学综述, 2012, 18(4): 620-621
作者姓名:周冬翠  裴志勇  毕磊
作者单位:中国人民解放军北京军区总医院干部病房一科,北京,100700
摘    要:
目的探讨高龄(≥70岁)冠心病患者心率变异性(HRV)的变化。方法对高龄冠心病组(300例)与正常对照组(198例)的电信号进行研究,观察比较时域指标:连续24 h内正常RR间期的标准差(SDNN)、全程记录中每5分钟正常RR间期平均值的标准差(SDANN)、相邻正常RR间期差值的均方根(RMSSD)、相邻RR间期差值>50 ms百分比(PNN50);频域指标:总功率(TP)、低频功率(LF)、高频功率(HF)。结果冠心病组HRV的SDNN、SDANN、RMSSD、PNN50、HF显著低于正常对照组(P<0.01),TP、LF比较差异无统计学意义(P>0.05)。结论高龄冠心病患者存在自主神经功能紊乱,迷走神经活性降低,交感神经活动相对增强。

关 键 词:高龄  冠状动脉粥样硬化性心脏病  心率变异性  自主神经功能

Analysis of Heart Rate Variability in 300 Elder Patients with Coronary Heart Disease
ZHOU Dong-cui , PEI Zhi-yong , BI Lei. Analysis of Heart Rate Variability in 300 Elder Patients with Coronary Heart Disease[J]. Medical Recapitulate, 2012, 18(4): 620-621
Authors:ZHOU Dong-cui    PEI Zhi-yong    BI Lei
Affiliation:.(Department One of Cadre′s Ward,Beijing Military General Hospital of Chinese PLA,Beijing 100700,China)
Abstract:
Objective To explore the diversity of heart rate variability(HRV)in eldeer patients(≥70years)with coronary heart disease.Methods Electrical signals of elder patients with coronary heart disease(n=300)and control group(n=198)were studied.Time domain index including SDNN,RMANN,PNN50,and frequency domain index including TP,LF,HF were observed.Results SDNN,SDANN,PNN50,HF of patients with coronary heart disease were lower than those of normal group significantly(P<0.01).TP,LF difference had no statistical significance(P>0.05).Conclusion Function disorder of autonomic nerve developed in elder patients with coronary heart disease,the activity of nerve vagus attenuates,the activity of sympathetic nervous accentuates relatively.
Keywords:Elder  Coronary atherosclerotic heart disease  Heart rate variability  Function of autonomic nerve
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