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| 医院药剂科的新药开发 | |
| 引用本文： | 袁继民,魏学彦,于连生. 医院药剂科的新药开发[J]. 药学实践杂志, 1999, 17(1): 48-50 |
| 作者姓名： | 袁继民 魏学彦 于连生 |
| 作者单位： | 上海市第六人民医院(史德懿)，上海医科大学药学院(刘怡)，第二军医大学药学院(张冬春) |
| 摘 要： | 目的：建立不经分离同时测定地塞米松磷酸钠及干扰组分尼泊金乙酯含量的测定方法。方法：以蒸馏水为空白，采用褶合光谱法。结果：平均回收率为１００８％，９９３９％；ＲＳＤ为１００％，０６１％。结论：本法方便准确，适用于紫外吸收有干扰的多组分制剂的常规分析。 |
| 关 键 词： | 复方地塞米松滴眼液；地塞米松磷酸钠；褶合光谱法；含量测定 |
| 收稿时间： | 1998-08-25 |
Application of convolution spectrometry method for determination of compound dexamethasone sodium phosphate eye drops |
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| Shi Deyi,Liu Yi,Zhang Dongchun. Application of convolution spectrometry method for determination of compound dexamethasone sodium phosphate eye drops[J]. The Journal of Pharmaceutical Practice, 1999, 17(1): 48-50 | |
| Authors: | Shi Deyi Liu Yi Zhang Dongchun |
| Abstract: | OBJECTIVE: To simultaneous determine the main-component dexamethasone sodium phosphate and the interfering-component ethylparaben in compound dexamethasone sodium phosphate eye drops without separation. METHODS: A convolution spectrometry method has been applied. RESULTS: The average recoveris and relative standard deviation were 100.8%,10%;9939%,061%,respectively. CONCLUSION: This method is convenient,accuracy and suitable for routine analysis of multicomponent preparation which has interference in ultraviolet spectrum. |
| Keywords: | compound dexamethasone sodium phosphate eye drops dexamethasone sodium phosphate convolution spectrum method quantiative determination |
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