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HPLC法测定复方对乙酰氨基酚注射液的含量
引用本文:李平,李敏. HPLC法测定复方对乙酰氨基酚注射液的含量[J]. 中国药师, 2002, 5(1): 33-34
作者姓名:李平  李敏
作者单位:江西省药品检验所,南昌,330046
摘    要:目的:建立高效液相色谱法测定复方对乙酰氨基酚注射液的含量。方法:采用HP ODS柱,以甲醇-水(45:55)为流动相,用紫外检测器于285nm波长处检测。结果:对乙酰氨基酚浓度在50~250μg·ml~(-1)范围内有良好的线性关系(r=0.9999),平均回收率为99.6%,安替比林在60~300μg·ml~(-1)范围内有良好的线性关系(r=0.9999),平均回收率为99.4%。结论:本法快速,简便,准确。

关 键 词:对乙酰氨基酚  安替比林  高效液相色谱法
修稿时间:2001-03-26

Content of Compound Paracetamol Injection Determined by HPLC
Li Ping,Li Min. Content of Compound Paracetamol Injection Determined by HPLC[J]. China Pharmacist, 2002, 5(1): 33-34
Authors:Li Ping  Li Min
Abstract:Objectives: To determine the content of compound paracetamol by HPLC. Method: ODS colunm was used, men-thanol-water(45:55) were served as mobile phase, it was detected at wavelength 285 nm with UV-detector, Result:Paracetamol concentration presented a good linear relation within a range of 50~250ug.ml-1, the average recovery was 99.6% . Antipyrine concentration presented a good linear relation within a range af 60~300ug.ml-1, the average recovery was 99.4% . Conclusion: This method is rapid, simple, and accurate.
Keywords:Paracetamol  Antipyrine  HPLC  
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