An in vitro assessment of certain cellular and humoral immune functions in patients with chronic acne

Testing of cellular and humoral immune functions was performed on nineteen patients with chronic acne. Eight patients had no detectable abnormality of cellular function, seven had low neutrophil motility and six had depressed mitogen induced lymphocyte transformation. Eight patients had raised levels of serum IgE, seven had positive CRP values and one had a total IgA deficiency. Following propranolol therapy five patients showed no evidence of clinical improvement and nine showed significant clinical and immunological improvement.