Critical features of periodontal flaps with regard to blood clot stability: A review |
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| Authors: | Muhammad Saad Shaikh Muhammad Sohail Zafar Flavio Pisani Mohid Abrar Lone Yasser Riaz Malik |
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| Affiliation: | 1. Department of Oral Biology, Sindh Institute of Oral Health Sciences, Jinnah Sindh Medical University, Karachi, 75510, Pakistan;2. Department of Restorative Dentistry, College of Dentistry, Taibah University, Madina Munawwarra, 41311, Saudi Arabia;3. Department of Dental Materials, Islamic International Dental College, Riphah International University, Islamabad, 44000, Pakistan;4. College of Medicine and Dentistry, MClinDent in Periodontology, Birmingham, B4 6BN, UK;5. Department of Oral Pathology, Sindh Institute of Oral Health Sciences, Jinnah Sindh Medical University, Karachi, 75510, Pakistan;6. Department of Community Dentistry, Sir Syed College of Medical Sciences for Girls, Karachi, 74200, Pakistan;7. Department of Preventive Dentistry (Dental Public Health), College of Dentistry, University of Hail, Hail, Saudi Arabia |
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| Abstract: | ![]()
BackgroundWound healing is a multifactorial procedure involving different cell types and biological mediators. The principles of wound healing are also applicable to periodontal tissues. The formation and stability of blood clots play a vital role in successful healing of wounds in periodontal tissues. The aim of the present review was to highlight the vital factors of periodontal flaps associated with blood clot stability.HighlightThe data on periodontal regeneration and wound healing have evolved greatly in light of several factors, including space for blood clots and blood clot stabilization. In periodontal osseous defects, the stability of blood clots seems critical to wound healing. If mechanical forces can be managed by wound stabilization, the gingival flap-tooth root interface may show connective tissue repair. However, compromised adhesion is susceptible to mechanical forces and can cause wound breakage and epithelialization.ConclusionThe presence of a thick blood clot may hinder the plasmatic circulation between the recipient bed and graft during the initial stage of healing, which is critical in cases of mucogingival surgery. Root conditioning can also determine the healing consequence by enhancing blood clot adhesion. |
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| Keywords: | Regeneration Wound healing Alveolar bone loss Gingival recession EMDs" },{" #name" :" keyword" ," $" :{" id" :" kwrd0045" }," $$" :[{" #name" :" text" ," _" :" enamel matrix derivatives CT" },{" #name" :" keyword" ," $" :{" id" :" kwrd0055" }," $$" :[{" #name" :" text" ," _" :" connective tissue PDL" },{" #name" :" keyword" ," $" :{" id" :" kwrd0065" }," $$" :[{" #name" :" text" ," _" :" periodontal ligament SPPF" },{" #name" :" keyword" ," $" :{" id" :" kwrd0075" }," $$" :[{" #name" :" text" ," _" :" simplified papilla preservation flap MWF" },{" #name" :" keyword" ," $" :{" id" :" kwrd0085" }," $$" :[{" #name" :" text" ," _" :" modified Widman flap GTR" },{" #name" :" keyword" ," $" :{" id" :" kwrd0095" }," $$" :[{" #name" :" text" ," _" :" guided tissue regeneration MPPF" },{" #name" :" keyword" ," $" :{" id" :" kwrd0105" }," $$" :[{" #name" :" text" ," _" :" modified papilla preservation flap MIST" },{" #name" :" keyword" ," $" :{" id" :" kwrd0115" }," $$" :[{" #name" :" text" ," _" :" minimally invasive surgical technique M-MIST" },{" #name" :" keyword" ," $" :{" id" :" kwrd0125" }," $$" :[{" #name" :" text" ," _" :" modified minimally invasive surgical technique SFA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0135" }," $$" :[{" #name" :" text" ," _" :" single flap approach DBBM" },{" #name" :" keyword" ," $" :{" id" :" kwrd0145" }," $$" :[{" #name" :" text" ," _" :" deproteinized bovine bone mineral sCTG" },{" #name" :" keyword" ," $" :{" id" :" kwrd0155" }," $$" :[{" #name" :" text" ," _" :" subepithelial connective tissue graft EPP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0165" }," $$" :[{" #name" :" text" ," _" :" entire papilla preservation IL" },{" #name" :" keyword" ," $" :{" id" :" kwrd0205" }," $$" :[{" #name" :" text" ," _" :" interleukin RCT" },{" #name" :" keyword" ," $" :{" id" :" kwrd0215" }," $$" :[{" #name" :" text" ," _" :" randomized controlled trial |
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