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The effect of patient positioning (prone or supine) on the dose received by small bowel in pelvic radiotherapy in rectal cancer patients
Authors:E. Esmati  M. Barzegartahamtan  A. Maddah  A. Alikhassi  V. Vaezzadeh  R. Mohammadpour
Affiliation:1. Radiation Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran;2. Clinical Research Center, Loghamn Hakim Hospital, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran;3. Cancer Institute, Imam Hospital, Tehran University of Medical Sciences, Tehran, Iran;4. Department of Biostatistics, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran;1. Department of radiation oncology, Jean-Perrin centre, 58, rue Montalembert, 63011 Clermont-Ferrand, France;2. Department of medical oncology, Jean-Perrin centre, 58, rue Montalembert, 63011 Clermont-Ferrand, France;3. Department of dermatology, Estaing university hospital centre, 1, rue Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand, France;4. INSERM U1240 IMoST, University of Clermont-Auvergne, 63000 Clermont-Ferrand, France;5. Centre d’investigation clinique UMR 501, 63001 Clermont-Ferrand, France;6. Department of clinical research, délégation recherche clinique et innovation, centre Jean-Perrin, 63011 Clermont-Ferrand, France;7. Department of medical physics, Jean-Perrin centre, 58, rue Montalembert, 63011 Clermont-Ferrand, France;8. Department of neurosurgery, Gabriel-Montpied university hospital centre, 58, rue Montalembert, 63011 Clermont-Ferrand, France;1. Department of radiation oncology, institut de cancérologie de l’ouest site Saint-Herblain, boulevard du Professeur-Jacques-Monod, 44800 Nantes Saint-Herblain, France;2. Department of medical physics, institut de cancérologie de l’ouest site Saint-Herblain, boulevard du Professeur-Jacques-Monod, 44800 Nantes Saint-Herblain, France;3. Department of urology, hôpital privé Océane, 3, rue du Dr-Joseph-Audic, 56000 Vannes, France;4. Department of urology, centre hospitalier universitaire de Nantes, place Ricordeau, 44000 Nantes, France;5. Department of urology, clinique Saint-Augustin, 1, rue Eugene-Tessier, 44000 Nantes, France;1. Department of Radiotherapy, Lucien Neuwirth Cancer Institute, Saint-Priest en Jarez, France;2. Research group in Cancer Biology, Research Branch, National Cancer Institute, Bogota, Colombia;3. Departement of Clinical Radiotherapy & Oncology, Babol University of Medical Sciences, Babol, Iran;4. Department of Radiation-Oncology, Shahid Behesti University Medial Sciences, Tehran, Iran;1. Department of Radiotherapy, Jean-Perrin Centre, 58, rue Montalembert, 63011 Clermont-Ferrand, France;2. Department of ENT Surgery, Centre Hospitalier Universitaire Hôpital Gabriel Montpied, 58, rue Montalembert, 63003 Clermont Ferrand, France;3. Department of Maxillo-Facial Surgery, Centre Hospitalier Universitaire Hôpital Estaing, 63003 Clermont-Ferrand, France;4. Department of Radiology, Centre Jean Perrin, 58, rue Montalembert, 63011 Clermont-Ferrand, France
Abstract:
PurposeThe small bowel is a main dose-limiting organ in pelvic radiotherapy in the patients with rectal cancer. Conventionally, pelvic radiotherapy of patients with rectal cancer is performed in the prone position.Material and MethodsThirty-nine patients underwent CT planning scan in the treatment position (20 patients in prone position group and 19 patients in supine position group). After radiation treatment planning optimization, the volumes of the irradiated small intestines were investigated.ResultsThe volume of irradiated small bowel was higher in the supine position (mean difference; 36,274 cm3). However, it was not statistically significant (P value = 0.187)ConclusionSupine position could be accepted for the patients undergoing preoperative rectal cancer chemo-radiation.
Keywords:Rectal cancer  Small bowel  Radiotherapy  Positioning  Cancer du rectum  Intestin grêle  Radiothérapie  Positionnement
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