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A role for mast cells and mast cell tryptase in driving neutrophil recruitment in LPS-induced lung inflammation via protease-activated receptor 2 in mice
Authors:de Almeida  Aline Dias  Silva   Irismara Sousa  Fernandes-Braga  Weslley  LimaFilho  Antônio Carlos Melo  Florentino   R odrigo Machado  Barra   Ayslan  de Oliveira Andrade  Luciana  Leite  M. Fátima  Cassali   Geovanni Dantas  Klein   André
Affiliation:1.Laboratory of Pain and Inflammation, Department of Pharmacology, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), Av. Presidente Ant?nio Carlos, 6627, Pampulha, Belo Horizonte, Minas Gerais, 31270-010, Brazil
;2.Department of Biochemistry and Immunology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil
;3.Department of Physiology and Biophysics, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil
;4.Department of Morphology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil
;5.Department of Pathology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil
;
Abstract:
Inflammation Research - This study aims to investigate the role of protease-activated receptor (PAR) 2 and mast cell (MC) tryptase in LPS-induced lung inflammation and neutrophil recruitment in the...
Keywords:
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