110例药品不良反应报告分析

目的:了解我院药品不良反应(ADR)发生的情况和特点,促进临床合理用药。方法:对我院2004年8月至2006年3月上报的110例ADR分别从报告科室、药品种类、给药途径、临床表现等方面进行统计分析。结果:ADR以临床住院病人发生的上报数量为101例,占总例数的91.8%;与抗感染用药有关的ADR最为多见,占总例数的75.5%;ADR表现以皮肤损害为主,其次为消化及神经系统损害,其中较严重的ADR有1例。结论:加强对抗感染药物合理应用的管理。

Analysis of adverse drug reactions in our hospital

Objective: The purpose of this feature is to heighten awareness of specific adverse drug reactions(ADRs),to discuss methods of prevention,and to promote reporting of ADRs.Methods: Data collected in our hospital from Aug.2004 to Mar.2006 were classified and analyzed statistically.Results: There were 101 records involving with inpatients,counted for 91.8%.The majority of records described non-serious events while 1 ADR defined as serious.The most frequently reported individual ADR was anti-infective agents(85%).The consistently high reporting rate of ADR were seen in 4 organs/ systems,dominating the first 3 places were damages of skin,digestive and neural system shock,which were caused by factors including the chemical property.Conclusion: the preparation process,non-rational use of drugs should be monitored from different levels so as to avoid ADRs.