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超选择性动脉溶栓治疗急性缺血性脑卒中临床研究
引用本文:杨杰,姜建东,杜颂伟,顾建平,潘雷,周俊山,袁存国,王景涛. 超选择性动脉溶栓治疗急性缺血性脑卒中临床研究[J]. 中国卒中杂志, 2006, 1(6): 394-396
作者姓名:杨杰  姜建东  杜颂伟  顾建平  潘雷  周俊山  袁存国  王景涛
作者单位:1. 210006,南京,南京医科大学附属南京第一医院神经内科
2. 210006,南京,南京医科大学附属南京第一医院介入放射科
摘    要:
目的评价超选择性动脉溶栓治疗急性缺血性脑卒中的疗效和安全性。方法选择2003年1月至2005年5月于本院进行超选择性动脉溶栓同时采用卒中登记方法收集的58例急性缺血性脑卒中患者,随访6个月,观察患者的预后。结果58例患者中并发脑出血6例(10.3%),其中症状性脑出血2例(3.4%)。1个月末、3个月末和6个月末分别死亡2例(3.4%)、4例(6.8%)和5例(9.3%)。3个月末和6个月未残疾或死亡例数分别为13例(22.4%)和9例(16.7%)。结论对选择的急性缺血性脑卒中患者进行超选择性动脉溶栓是有效和安全的。

关 键 词:缺血性脑脑血管病  动脉溶栓  登记
文章编号:1673-5765(2006)06-0394-03
修稿时间:2006-05-20

Superselective Intra-arterial Thrombolysis for Acute Ischemic Stroke
YANG Jie JIANG Jian-dong DU Song-wei. Superselective Intra-arterial Thrombolysis for Acute Ischemic Stroke[J]. Chinese Journal of Stroke, 2006, 1(6): 394-396
Authors:YANG Jie JIANG Jian-dong DU Song-wei
Affiliation:YANG Jie JIANG Jian-dong DU Song-wei.Department of Neurology,Nanjing Fist Hospital Affiliated to Nanjing Medical University,Nanjing 210006,China
Abstract:
Objective To evaluate the effect and safety ofsuperselective intra-arterial thrombolysis(SIAT) for acute ischemic stroke(AIS).Methods Selected AIS patients were included for SLAT.Through stroke registry,patients' clinical and imaging information were collected at the same time,and outcomes were followed for 6 months prospectively.Results SlAT were carried out on 58 AIS patients during January 2003 to May 2005,Intracranial hemorrhage were happened to 6(10.3%) patients,2(3.4%) of them were symptomatic.The mortality at the end of I month,3 month and 6 month were 3.4%, 6.8% and 9.3% respectively.The mortality/disability at the end of 3 month and 6 month were 22.4% and 16.7% respectively. Conclusions SIAT is effective and safe for selected AIS patients.
Keywords:ischemic stroke  intra-arterial thrombolysis  stroke registry
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