无水乙醇在颅内巨大高血运脑膜瘤中的应用

目的 评估无水乙醇在颅内巨大高血运脑膜瘤手术中的止血作用及脑膜瘤的切除效果. 方法 四川省肿瘤医院颅脑外科自2004年9月至2008年10月对12例颅内巨大高血运脑膜瘤患者采用术中无水乙醇(8.5～27 mL,平均11.2 mL)注射止血后,显微镜下行肿瘤全切术. 结果 脑膜瘤注射区不同程度变白.瘤体变硬,表面及切面出血明显减少甚至停止.本组病例术中出血约48～154mL,平均67mL;手术全切11例,次全切1例,全切率91.6%;术后无任何手术并发症发生. 结论 高血运脑膜瘤手术中注射无水乙醇止血,简便易行,效果良好,值得推广.

Application of absolute alcohol in operations for giant meningiomas with rich blood supply

Objective To evaluate the effectiveness of absolute alcohol in hemostasis in surgical resection of giant meningiomas with rich blood supply. Methods Twelve patients with giant meningiomas with rich blood supply were injected with absolute alcohol (8.5-27 mL, mean 11.2 mL) in the operations, and the tumors were resected under microscope. Results The tissues in the injection areas turned white and the tumors became hardened after the injection. The bleeding of the tumor surface and section was obviously decreased or even stopped. The quantities of bleeding were 48-154 mL in the operations, with an average of 67 mL. Total tumor resection was achieved in 11 patients (91.6%) and partial resection in 1 patient. No complications associated with the surgery were found in these cases. Conclusion Injection of absolute alcohol for hemostasis in surgical removal of giant meningiomas with rich blood supply is convenient and effective and can be widely applied in clinical practice.