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| 妊高征胎盘组织过氧化脂质及超氧化物歧化酶活性的变化 | |
| 引用本文： | 廖予妹,耿正惠,李小姝. 妊高征胎盘组织过氧化脂质及超氧化物歧化酶活性的变化[J]. 河南医学研究, 1993, 0(2) |
| 作者姓名： | 廖予妹 耿正惠 李小姝 |
| 作者单位： | 河南医科大学第二附属医院妇产科，河南医科大学第二附属医院妇产科，河南医科大学第二附属医院妇产科 郑州 450003，郑州 450003，郑州 450003 |
| 摘 要： | 本文测定32例正常妊娠晚期,28例中重度妊娠高血压综合征(妊高征)孕妇的胎血组织过氧化脂质(LPO)水平及超氧化物歧化酶(SOD)活性。结果表明,妊高征组的胎盘组织LPO 水平显著升高,而其 SOD 活性显著下降。在正常孕妇、中度及重度妊高征三组中,胎盘组织 LPO/SOD 比值依次下降,各组之间差异显著。提示,妊高征胎盘组织中可能存在着氧化与抗氧化反应间的失平衡,对妊高征患者的治疗,除给以镇静、解痉药物外,尚需辅以疏通微循环及抗氧化作用的药物,可有利病情的改善。 |
| 关 键 词： | 妊高征 胎盘 过氧化脂质 超氧化物歧化酶 |
CHANGES OF LIPID PEROXIDES AND SUPEROXIDE DISMUTASE ACTIVITIES IN PLACENTAE OF PREGNANCY INDUCED HYPERTENSION |
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| Liao Yu-mei Geng Zheng-hui Li Xiao-shu. CHANGES OF LIPID PEROXIDES AND SUPEROXIDE DISMUTASE ACTIVITIES IN PLACENTAE OF PREGNANCY INDUCED HYPERTENSION[J]. Henan Medical Research, 1993, 0(2) | |
| Authors: | Liao Yu-mei Geng Zheng-hui Li Xiao-shu |
| Abstract: | The lipid peroxides(LPO)and superoxide dismutase(SOD)activities were observed in placentae of 25 normal and 28 moderate or severe PIH gravidae.The placental LPO levels were signifi- cantly higher and SOD activites were significantly lower in patients with moderate or severe PIH than that in normal pregnancy women(P<0.05,P<0.01).The placental SOD/LPO ratios fallen gradual- ly in normal pregnancy women,moderate and severe PIH patients,there was significant difference a- mony three groups(P<0.01).The results suggested that there possibly existed the imbalance of per- oxide/antioxide in placentae of PIH patients. |
| Keywords: | pregnancy induced hypertension placenta lipid peroxides superoxide dismutase |
| 本文献已被 CNKI 等数据库收录！ | |