| 焦炉工人职业性肺癌病因再探讨 |
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| 引用本文： | 耿秀娥,程海明,周慧,王玉民. 焦炉工人职业性肺癌病因再探讨[J]. 工业卫生与职业病, 2003, 29(3): 144-145 |
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| 作者姓名： | 耿秀娥 程海明 周慧 王玉民 |
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| 作者单位： | 山西省疾病预防控制中心,山西,太原,030012;山西省疾病预防控制中心,山西,太原,030012;山西省疾病预防控制中心,山西,太原,030012;山西省疾病预防控制中心,山西,太原,030012 |
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| 基金项目： | 山西省重点攻关课题92(152) |
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| 摘 要： | 目的 进一步探讨焦炉工人职业性肺癌的病因。方法 采用多种致癌因子诱发小鼠肺癌的实验。结果 二苯并[a,h]蒽的致癌作用强于苯并[a]芘,五环烃同焦尘相复合后,致癌作用呈现相加效应。结论 五环烃,尤其是二苯并[a,h]蒽,作为多环芳烃致癌原的代表,是焦炉工人职业性肺癌的主要病因。
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| 关 键 词： | 职业性肺癌 焦炉 二苯并[a h]蒽 五环烃 |
| 文章编号： | 1000-7164(2003)03-0144-02 |
| 修稿时间： | 2002-09-10 |
A Further Study on Etiology of Occupational Lung Cancer among Coke Oven Workers |
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| GENG Xiu e,CHENG Hai ming,ZHOU Hui,et al. A Further Study on Etiology of Occupational Lung Cancer among Coke Oven Workers[J]. Industrial Health and Occupational Diseases, 2003, 29(3): 144-145 |
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| Authors: | GENG Xiu e CHENG Hai ming ZHOU Hui et al |
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| Abstract: | Objective To further explore the etiology of occupational lung cancer among coke oven workers. Methods Induce mice lung cancer by different kinds of carcinogens.Results DB[a,h]A is more carcinogenic than B[a]P . Carcinogenic effect might be increased by exposure to pentacyclic hydrocarbons and coke dust simultaneously.Conclusions The pentacyclic hydrocarbons,especially the DB[a,h]A, a representative carcinogen of this group,might be the main carcinogen for occupational lung cancer among coke oven workers. |
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| Keywords: | Occupational lung cancer Coke oven DB[a h]A Pentacyclic hydrocarbon |
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