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| T抗原单克隆抗体法在大肠癌筛检中的应用初探 | |
| 引用本文： | 罗定存 戴洪进. T抗原单克隆抗体法在大肠癌筛检中的应用初探[J]. 中国癌症杂志, 1998, 8(4): 256-257 |
| 作者姓名： | 罗定存 戴洪进 |
| 作者单位： | 浙江省温州市第二人民医院!温州325028 |
| 基金项目： | 温州市卫生局科技基金 95004(95) |
| 摘 要： | 目的 探讨T抗原单克隆抗体法在大肠癌筛检中的临床价值.方法 同时采用T抗原单克隆抗体法和半乳糖氧化酶法检测207例直肠粘液中的T抗原.结果 T抗原单克隆抗体法和半乳糖氧化酶法的敏感性和特异性分别为69.2%、67.3%和64.2%、65.6%,两者的筛检价值无明显差别.结论T抗原单克隆抗体法对大肠癌筛检有较大临床价值,且操作简便. |
| 关 键 词： | 肠肿瘤 T抗原 半乳糖氧化酶类 |
A STUDY ON THE SCREENING OF LARGE INTESTINAL CARCINOMA BY T-ANTIGEN MONOCLONAL AN-TIBODY METHOD |
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| Luo Dingcun,Dai Hongjing,Ni Yaozhong,et al.. A STUDY ON THE SCREENING OF LARGE INTESTINAL CARCINOMA BY T-ANTIGEN MONOCLONAL AN-TIBODY METHOD[J]. China Oncology, 1998, 8(4): 256-257 | |
| Authors: | Luo Dingcun Dai Hongjing Ni Yaozhong et al. |
| Affiliation: | Luo Dingcun,Dai Hongjing,Ni Yaozhong,et al. Department of Surgery Wenzhou Second People's Hospital,Wenzhou 325028 |
| Abstract: | PURPOSE To investigate the clinical value of the T-antigen monoclonal antibody method on screening of large intestinal carcinoma. METHODS The T-antigen monoclonal antibody method and the galactose oxidase method were simultaneously used to detect T-antigen in large intestinal mucus of 207 cases. RESULTS There was not obvious difference in screening value between the T-antigen monoclonal antibody method and the galactose oxidase method, for that they had similar sensitivity (69. 2%, 67. 3%) and specificity (64. 2%, 65. 6%) in diagnosis of large intestinal carcinoma. CONCLUSION The T-antigen monoclonal antibody method was convenient, eligible and valuable on screening of large intestinal carcinoma. |
| Keywords: | Intestinal neoplasms T-antigen Galactose oxidase |
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