急性心肌梗死患者血清心肌肌钙蛋白I异常变化与近期预后的关系

目的探讨急性心肌梗死（AMI）患者血清心肌肌钙蛋白I（cTnI）异常变化与近期预后的关系。方法入选AMI患者46例，发病后分别于7、10、14d采血测定血清cTnI，将患者分为A组28例，血清cTnI变化符合AMI正常规律；B组18例，血清cTnI变化异常，延迟下降或下降后又升高，随诊3个月观察两组患者心血管事件的发生情况。结果B组患者的恶性心律失常、梗死后心绞痛、心力衰竭、死亡等心血管事件发生率明显高于A组。差异有统计学意义（P〈0．01）。结论AMI患者血清cTnI异常变化可预测近期不良心血管事件的发生。

, Relationship between abnormal change of serum cardiac troponin I and short-term prognosis in patients with acute myocardial infarction

Objective To explore the relationship between abnormal change of serum cardiac troponin I （cTnI）and short-term prognosis in patients with acute myocardial infarction （AMI）.nethods 46 patients with AMI were selected and the level of serum cTnI of them were measured on days 7,10,14 after onset.The patients with normal change of serum cTnI were assigned to group A（38 cases）and the patients who showed abnormal changes of serum cTnI level,ei- ther delayed drop or increase after decreasing,were assigned to group B （28 cases）.All the patients in two groups were followed up for three months and cardiovascular events were observed.Results The incidence rate of cardiovascular events including malignant arrhythmia,post-infarction angina pectoris,cardiac failure and death in Group B was higher than that in group A,with statistical difference （P〈0.01）.Conclusion The abnormal change of serum cTnI level of pa- tients with AMI is a predictor of short-time adverse cardiovascular events.