Inhibin-betaA and -betaB subunits in normal and malignant glandular epithelium of uterine cervix and HeLa cervical cancer cell line |
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Authors: | Alexander Burges Naim Shabani Ansgar Brüning Ioannis Mylonas |
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Affiliation: | 1.Department of Obstetrics and Gynaecology,Ludwig-Maximilians-University Munich,Munich,Germany;2.Department of Obstetrics and Gynaecology,Klinikum Neuperlach,Munich,Germany;3.1st Department of Obstetrics and Gynaecology,Ludwig-Maximilians-University Munich,Munich,Germany |
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Abstract: |
Introduction Inhibins, dimeric peptide hormones composed of an alpha-subunit and one of two possible beta-subunits (betaA or betaB), exhibit substantial roles in human reproduction and in endocrine-responsive tumors. However, it is still unclear if normal and cancerous cervical glandular epithelial cells as well as cervical cancer cell lines of glandular origin express the inhibin-betaA and -betaB subunits. |
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