| 抗ENA抗体与抗核抗体的相关性 |
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| 引用本文： | 龚岚. 抗ENA抗体与抗核抗体的相关性[J]. 职业与健康, 2010, 26(3): 356-357 |
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| 作者姓名： | 龚岚 |
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| 作者单位： | 江苏省无锡市第二人民医院,214000 |
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| 摘 要： | 目的探讨抗核抗体（ANA）荧光核型与抗可提取性核抗原抗体（ENA）之间的相关性。方法ANA采用间接免疫荧光法检测，抗ENA抗体采用欧蒙免疫斑点法检测，检测结果采用双盲对照法分析。结果312例抗ENA抗体阳性病例ANA的阳性率为93．3％，荧光核型主要以颗粒型为主，抗Scl-70抗体阳性时则以核仁型为主，抗Jo-1抗体阳性的ANA荧光核型比较分散。另外检测的124例ANA阳性病例中，抗ENA抗体常规6项阳性率为71．8％。结论抗ENA抗体类型与ANA荧光核型之间没有绝对的规律，临床检测自身抗体时需将两者结合分析。
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| 关 键 词： | 抗核抗体 抗可提取性核抗原抗体 荧光核型 相关性分析 |
Correlation between ANA and ENA |
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| GONG Lan. Correlation between ANA and ENA[J]. Occupation and Health, 2010, 26(3): 356-357 |
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| Authors: | GONG Lan |
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| Affiliation: | GONG Lan(Wuxi Second People's Hospital,Jiangsu,214000,China) |
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| Abstract: | [Objective]To study the correlation between fluorescent karyotype of antinuclear antibody(ANA)and antiextractable nuclear antigen antibody(ENA).[Methods]ANA was detected by indirect immunofluorescence assay,anti-ENA antibody was detected by EUROASSAY,the results were analyzed by double-blind control method.[Results]Of all 312 anti-ENA antibody positive cases,the positive rate for ANA was 93.3%,main of them were granular pattern.The positive cases of anti-Scl-70 were nucleolar pattern,while the fluorescent k... |
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| Keywords: | Antinuclear antibody(ANA) Antiextractable nuclear antigen antibody(ENA) Fluorescent karyotype Correlation analysis |
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