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氯乙烯作业工人肝脏损害三年动态观察
引用本文:侯光萍,任永清,任恒岩. 氯乙烯作业工人肝脏损害三年动态观察[J]. 潍坊医学院学报, 1988, 0(2)
作者姓名:侯光萍  任永清  任恒岩
作者单位:潍坊市人民医院,潍坊市人民医院,潍坊化工厂
摘    要:1981年~1983年对某化工厂氯乙烯车间的生产条件进行了改善,使车间空气中氯乙烯浓度基本达到国家最高容许浓度(30mg/m~3),对改善前后的氯乙烯职业危害进行了动态观察。结果证明氯乙烯肝脏损害与车间浓度、年龄、工龄有关(P<0.05),与工种无关;三年间断肝功化验,无转氨酶增高者,提示肝脏损害以慢性纤维化为主,这点与传染性肝炎不同;未发现肝血管肉瘤及癌变,无指端溶骨症。一例双指呈囊样改变,是否为指端溶骨症的早期改变,有待进一步观察。

关 键 词:肝脏损伤  氯乙烯  致癌物质

THREE YEARS EXAMINATION OF HEPATIE DAMAGE IN VINYL CHLORIDE EMPLOYED WORKER
Hou Guangping,et al. THREE YEARS EXAMINATION OF HEPATIE DAMAGE IN VINYL CHLORIDE EMPLOYED WORKER[J]. Journal of Weifang Medical College, 1988, 0(2)
Authors:Hou Guangping  et al
Affiliation:Weifang People's Hospital
Abstract:During 1981~1983, we inproved the environmental condition of vinyl chloride workshop in a cartain chemical industry factory, and make density of vinyl chloride within the limits of national passibly (30mg/m~3). Around the improvement, we dynamatic examined the effect of vinyl chloride on hepatic damage, the results indicated that vinyl chloride was closed related to the density, age and length of servics (P<0.05); but no related to type of work in production. In test of hepatic functions, transaminase kept in ordinory level, so suggest the chief damage of liver is chronic fibrosis, and different from infectious hepatitis. No found out hemasercomas and carcinoma of the liver; acroosteolysis also none. However, in one case, we found cystica changes in double finger,whether or not the early state change of acro-ostelysis still inquire further.
Keywords:hepatic damage  vinyl chloride  carcinogen
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