DWI和ADC图在前列腺癌诊断中的应用研究

目的探讨和比较不同b值DWI和ADC图在前列腺癌诊断中的应用价值。方法收集行前列腺MRI检查的前列腺癌疑诊患者62例,所有病例均以病理学诊断为金标准,研究对象均行不同b值DWI检查,分析比较不同b值DWI和ADC图对前列腺癌的诊断敏感性和特异性。结果前列腺癌患者35例。b=500s/mm2,DWI对前列腺癌的诊断敏感性和特异性分别为54.3%和70.4%;b=1000s/mm2,DWI和ADC图对前列腺癌的诊断敏感性和特异性分别为80.0%和77.8%、88.6%和85.2%。b=1000s/mm2时,DWI对前列腺癌的诊断敏感性、特异性均高于b=500s/mm2,其中敏感性存在统计学差异;当b=1000s/mm2时,ADC图对前列腺癌的诊断敏感性和特异性高于DWI,但均不存在统计学差异。结论当b=1000s/mm2时,DWI和ADC图对前列腺癌均有较高的诊断价值;而b=500s/mm2时,DWI对前列腺癌的诊断敏感性较差。

Application of DWI and ADC Maps in the Diagnosis of Prostate Cancer

Objective To explore and compare the value of DWI and ADC maps with different b values in the diagnosis of prostate cancer. Methods Sixty-two patients with clinical suspicion of prostate cancer were scanned with MRI, all cases were pathological diagnosis as the gold standard, and they underwent DWI examination with different b values. The sensitivity and specificity for the diagnosis of prostate cancer were evaluated by DWI and ADC maps. Results 35 patients were confirmed histopathologically to have prostate adenocarcinoma. DWI at a b-value of 500s/mm2 were found to have a sensitivity of 54.3% and a specificity of 70.4%. DWI at a b-value of 1000s/mm2 were found to have a sensitivity of 80.0% and a specificity of 77.8%. ADC maps at a b-value of 1000s/mm2 were found to have a sensitivity of 88.6% and a specificity of 85.2%. DWI at a b-value of 1000s/mm2 had higher sensitivity and specificity than DWI at a b-value of 500s/mm2, the sensitivity was statistically different between them. The sensitivity and specificity were higher for ADC maps at a b-value of 1000s/mm2 compared to DWI at a b-value of 1000s/mm2, but there were not statistically different. Conclusions DWI and ADC maps at a b-value of 1000s/mm2 have a high value in the diagnosis of prostate cancer; DWI at a b-value of 500s/mm2 have a low sensitivity in the diagnosis of prostate cancer.