| Gastric Mucosal Blood Flow and Acid Secretion in Rats |
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| 引用本文： | 李兆申,周岱云,许国铭. Gastric Mucosal Blood Flow and Acid Secretion in Rats[J]. 中国人民解放军军医大学学报, 1989, 0(3) |
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| 作者姓名： | 李兆申 周岱云 许国铭 |
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| 作者单位： | Department of Gastroenterology Changhai Hospital Second Military Medical University Shanghai，Department of Gastroenterology Changhai Hospital Second Military Medical University Shanghai，Department of Gastroenterology Changhai Hospital Second Military Medical University Shanghai |
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| 摘 要： | The relationship between gastric mucosal blood flow (GMBF) and gastric acid secretionwere studied in rats by using secretory stimulant (pentagastrin)and inhibitor(cimetidine). GMBFwas measured by Laser Doppler flowmetry (LDF) and gastric mucosal pH determined by microglasspH electrode. GMBF increased and gastric mucosal pH decreased significantly after intravenous injec-tion of 6μg/kg of pentagastrin; nevertheless GMBF decreased and gastric mucosal pH increasedmarkedly after intravenous administration of 100mg/kg of cimetidine. This indicates that pentagastrincan increase GMBF and gastric acid secretion, and cimetidine can decrease GMBF and gastric acidsecretion in rats, proving the close relationship between GMBF and gastric acid secretion in rats.
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Gastric Mucosal Blood Flow and Acid Secretion in Rats |
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| Li Zhaoshen,Zhou Daiyun,Xu Guoming. Gastric Mucosal Blood Flow and Acid Secretion in Rats[J]. Journal of Medical Colleges of PLA(China), 1989, 0(3) |
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| Authors: | Li Zhaoshen Zhou Daiyun Xu Guoming |
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| Affiliation: | Li Zhaoshen,Zhou Daiyun,Xu Guoming,Department of Gastroenterology,Changhai Hospital,Second Military Medical University,Shanghai |
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| Abstract: | |
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| Keywords: | gastric mucosal blood flow gastric acid secretion H_2 antagonist Laser Doppler flowmetry |
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