Ephrin-B2在乳腺癌组织中的表达及临床意义 |
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引用本文: | 赵微,冯冲. Ephrin-B2在乳腺癌组织中的表达及临床意义[J]. 牡丹江医学院学报, 2012, 33(6): 3-5 |
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作者姓名: | 赵微 冯冲 |
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作者单位: | 佳木斯大学基础医学院;牡丹江医学院附属红旗医院 |
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摘 要: | 目的:探讨Ephrin-B2.在乳腺癌组织中的表达及临床意义。方法:采用免疫组织化学法检测50例乳腺癌组织和20例正常乳腺组织中Ephrin-B2的蛋白表达,并结合临床病理特征进行相关统计学分析。结果:Ephrin-B2蛋白在乳腺癌中的表达明显高于正常组织,并且与乳腺癌病理分型和淋巴结转移密切相关(P〈0.05),而与其他病理因素无关(p〉0.05)。结论:Ephrin-B2在乳腺癌的发展与转移中发挥重要作用,为Ephrin-B2为靶点的癌症治疗提供新的思路。
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关 键 词: | 乳腺癌 Ephrin-B2 |
EPHRIN-B2 EXPRESSION AND CLINICAL SIGNIFICANCE IN BREAST CANCER |
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Affiliation: | Zhao Wei etal(Jiamusi Medical University,Heilongjiang Province,154007,China) |
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Abstract: | Objective :To investigate the expression and clinical significance of Ephrin - B2 in breast cancer. Methods:Using SABC immunohistochemical methods to detect the expression of Ephrin - B2 in 50 patients with breast carcinoma and 20 normal tissues in healthy people. Results: EPHRIN - B2 in Breast carcinoma was significantly higher than normal tissue. And metastasis of brsast carcino- ma. Conclusion: Ephrin - B2 might coordinatively cause the genesis of breast carcinoma. |
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Keywords: | Breast carcinoma Ephrin- B2 |
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