MR动态增强三变量对垂体微腺瘤的诊断价值

目的 应用Logistic回归和ROC曲线探讨MR动态增强扫描变量达峰时间、强化率及斜率在垂体微腺瘤诊断中的应用价值.方法 正常垂体者30例,垂体微腺瘤患者30例,全部行MR动态增强扫描,三个变量值,通过ROC曲线分析达峰时间、强化率、斜率及Logistic回归结果的ROC曲线下面积.结果 达峰时间ROC曲线下面积0.896,强化率曲线下面积0.643,强化斜率曲线下面积0.868,三个变量联合ROC曲线下面积0.907.结论 动态增强扫描达峰时间、强化斜率对垂体微腺瘤诊断价值较高,三变量联合诊断价值高于单变量.

Diagnostic value of three variances of MR dynamic enhancement on pituitary microadenoma

Objective To assess the diagnostic value of peak time, enhancement rate and slope of MR dynamic en- hancement on pituitary microadenoma by logistic regression and ROC curve. Method 30 people with normal pituita- ry and 30 patients with pituitary microadenoma undertook MR dynamic enhancement scanning, and analyzed the ROC curve of peak time, slope and enhancement rate and compared the area under the ROC curve of logistic regression. Result ROC analysis showed that the area under ROC curve of peak time, curve of enhancement rate ,curve of enhance slope was 0. 896, 0. 643 and 0. 868, and the area under combined ROC curve of 3 variances was 0. 907. Conclusion Peak time, slope of MR dynamic enhancement is valuable in diagnosis of pituitary microadenoma. The diag- nostic value of three variances are higher than single variance.