心肌肌钙蛋白与先天性心脏病介入损伤的研究进展

先天性心脏病(CHD)介入治疗能否引起心肌损伤是介入学科关注的重点之一,心肌肌钙蛋白(cTn)以其高度特异性和敏感性成为衡量心肌损伤的特异指标.CHD的类型、缺损及封堵器的大小、瓣膜狭窄的程度、患儿年龄和体质量等可影响肌钙蛋白的变化,故可作为研究心肌损伤的相关危险因素.

Progress of cardial troponin and the injury after transcatheter closure of congenital heart disease

That thranscatheter therapy of congenital heart disease (CHD) can cause myocardial injury is one of the focal points of attention in disciplines. Cardiac troponin (cTn) with its high specificity and sensitivity becomes special myocardial injury measure indicators. The types of CHD, the sizes of defect and occluder, the degree of stenosis, and the patients age and body weight, with their influence due to the concentrations of cTn,can be tested as associated risk factors of the myocardial injury.