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允许性高碳酸血症对呼吸循环系统的影响
引用本文:杨田军,刘宝.允许性高碳酸血症对呼吸循环系统的影响[J].国际呼吸杂志,2011,31(2):151-154.
作者姓名:杨田军  刘宝
作者单位:安徽省立医院ICU,合肥,230001
摘    要:允许性高碳酸血症是肺保护性通气策略的被动结果.早期认为动脉血二氧化碳分压升高及由之引起的酸中毒会导致心血管恶性事件发生率增高.而近期的研究结果显示高碳酸血症本身对脏器有保护作用,从而引入了治疗性高碳酸血症的概念.高碳酸血症可显著影响呼吸循环功能.该文从高碳酸血症对血管张力、肺泡通透性的影响等几个方面作一综述.

关 键 词:允许性高碳酸血症  急性呼吸窘迫综合征  呼吸机相关性肺损伤

Effect of permissive hypercapnia on respiratory circulatory system
YANG Tian-jun,LIU Bao.Effect of permissive hypercapnia on respiratory circulatory system[J].International Journal of Respiration,2011,31(2):151-154.
Authors:YANG Tian-jun  LIU Bao
Abstract:Permissive hypercapnia is a passive result of lung protective ventilation strategy. Earlier studies thought that increased arterial carbon dioxide pressure and acidosis caused by it could lead to increased incidence of cardiovascular vicious events. But recent studies have shown that hypercapnia has a protective effect on organs,thereby the concept of therapeutic hypercapnia is introduced. Hypercapnia can significantly affect respiratory circulatory functions. This article reviews the effects of hypercapnia on vascular tone,alveolar permeability.
Keywords:Permissive hypercapnia  Acute respiratory distress syndrome  Ventilator-induced lung injury
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