抗幽门螺杆菌感染药物治疗消化性胃溃疡的临床效果观察

目的探讨抗幽门螺杆菌感染药物治疗消化性胃溃疡的临床效果。方法 40例消化性胃溃疡患者随机平分为2组,治疗组采用基于奥美拉唑的三联疗法治疗,对照组采用基于雷钡拉唑的三联疗法治疗。结果治疗后治疗组的有效率为90.0%,对照组为85.0%,2组有效率差异无统计学意义(P>0.05)。治疗前2组血清NO无明显差异(P>0.05)。治疗后2组NO都有明显上升(P<0.05),2组相比也无显著性差异(P>0.05)。结论抗幽门螺杆菌感染药物治疗消化性胃溃疡都能取得较好的效果,能减少血清NO含量,值得推广应用。

Observation of Clinical Effect of Treating Patients Suffering from Peptic Gastric Ulcer with Anti-Infection Drug against-Helicobacter Pylori

Objective To explore clinical effect of treating patients suffering from peptic gastric ulcer with anti-infection drug against Helicobacter pylori.Methods 40 patients with peptic gastric ulcer were randomly divided into Treatment Group and Control Group.Treatment Group was treated with omeprazole-based triple therapy;on the other hand,Control Group was treated with rabeprazole-based triple therapy.Results After treatment,both groups demonstrated no significant differences in drug effectiveness by comparison(P>0.05).Both groups had no significant differences in serum No.(P>0.05) before treatment.Throughout treatment,both groups had higher serum No.(P<0.05),showing no significant differences by comparison(P>0.05).Conclusion It is worth promoting to treat patients suffering from peptic gastric ulcer with anti-infection drug against Helicobacter pylori for it has good curative effects and reduces serum No.content concurrently.