肝动脉化疗栓塞对肝癌术后高危复发患者的疗效分析

目的 探讨原发性肝癌切除术后肝动脉化疗栓塞(TACE)的疗效.方法 将86例肝癌术后的高危复发患者分为干预组(TACE治疗组)和对照组(未行TACE治疗组).术后高危复发的标准为:①单发病灶>5 cm;②病灶数≥2处;③术后病理检查有镜下癌栓.符合其中任意一条为术后高危复发患者.干预组术后1～2月行TACE治疗.结果 ...

Effect of postoperative transarterial chemoemblization on recurrence in high-risk patients after surgical resection of hepatocellular carcinoma

Objective To explore the effect of postoperative transarterial chemoemblization (TACE) on recurrence of high-risk patients after resection of hepatocellular carcinoma. Methods Eighty-six high-risk patients after surgical resection of hepatocellular carcinoma were divided into TACE group and control group. Forty-seven patients in TACE group received TACE 1 ～ 2 months after resection, the other 39 patients in control group were treated without TACE. The high-risk factors were defined as single tumor > 5 cm or tumor nodules ≥2 or with the presence of microscopic tumor thrombus. Results Recurrent rate of TACE group was higher than that of control group at 12 th month post-resection(32.43% vs 17.95%, P < 0.05), but there was no significant difference on recurrent rates between two groups at 24th month post-resection (48.94% vs 48.72%, P = 0.8224).The median survival time was 26 months in TACE group which was comparable to 22 months in control group (P = 0.0498). Conclusion Postoperative TACE has no effect on recurrence, but may be of benefit to detect residual tumor and prolong the median survival time.