First Report of Cerebral Venous Thrombosis Following Inactivated-Virus Covid Vaccination (Sinopharm and Sinovac) |
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| Affiliation: | 1. Neurosurgical Service, KK Women''s and Children''s Hospital, 100 Bukit Timah Road, 229899 Singapore;2. Department of Neurosurgery, National Neuroscience Institute, Singapore;3. SingHealth Duke-NUS Neuroscience Academic Clinical Program, Singapore, 11 Jalan Tan Tock Seng, 308433 Singapore;1. Department of Neurosurgery and Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Jiangsu, China;2. Department of Neurosurgery, Brigham and Women''s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA;3. Department of Neurosurgery, Amsterdam University Medical Centers, Amsterdam, the Netherlands;4. Department of Radiology, Brigham and Women''s Hospital, Boston, MA, USA;5. Reveal Pharmaceuticals, Cambridge, MA, USA;6. Research Information Systems and Computing, Mass General Brigham, Boston, MA, USA;7. Boston Children''s Hospital Informatics Program, Boston, MA, USA;8. Department of Computer Science, Loyola University, Chicago, IL, USA;9. Division of Rheumatology, Immunology and Allergy, Brigham and Women''s Hospital, Boston, MA, USA;10. Department of Neurology, Massachusetts General Hospital, Boston, MA, USA;11. Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA;12. Channing Division of Network Medicine, Brigham and Women''s Hospital, Boston, MA, USA;1. Department of Neurology, Korea University Ansan hospital, Korea University College of Medicine, Ansan, South Korea;2. Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea;3. Department of Radiology and Research, Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea;1. Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan;2. Department of Neurology, Chikamori Hospital, Kochi, Japan;3. Department of Disease Model, Research Institute of Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan;4. Department of General Dentistry, Hiroshima University Hospital, Hiroshima, Japan;5. Department of Neurology, Suiseikai Kajikawa Hospital, Hiroshima, Japan;1. Department of Neuroradiology, ASST Sette Laghi, University of Insubria, Varese, Italy;2. Division of Neurosurgery, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy;3. Neurosurgery Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, Brescia, Italy;4. Associate Professor, Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India;5. Department of Department of Neuroradiology, ARNAS Civico di Palermo, Palermo, Italy;6. Department of Anesthesiology and Resuscitation, ASST Sette Laghi, Varese, Italy;7. Department of Neuroradiology, ASST Monza, Monza, Italy;8. Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota, USA;1. Department of Neurosurgery, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan;2. Neuroendovascular Therapy Center, Shinshu University Hospital, 3-1-1 Asahi, Matsumoto 390-8621, Japan |
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| Abstract: | ![]()
Cerebral venous thrombosis (CVT) is an uncommon cerebrovascular disease, which has been reported with covid infection as well as covid vaccines, particularly AstraZeneca and Janssen vaccines. We present four consecutive cases of CVT after receiving either Sinopharm or Sinovac vaccine, both of which are composed of an inactivated-virus. All the patients recovered well with anticoagulation and discharged with a good functional outcome. This is the first case series reporting CVT following the administration of these vaccines. |
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