头孢噻肟钠对肝硬化伴上消化道出血患者院内感染的防治效果评价

目的 分析头孢噻肟钠对肝硬化伴上消化道出血患者院内感染的防治作用.方法 选取2017年6月-2018年6月,某医院收治肝硬化伴上消化道出血患者80例为研究对象,采取随机表法把所有患者分为对照组(40例)与观察组(40例),给予对照组常规治疗,观察组则在常规治疗的基础上采用头孢噻肟钠进行治疗,比较两组患者的感染发生率、再...

Preventive and therapeutic effects of cefotaxime sodium on nosocomial infection in patients with liver cirrhosis complicated with upper gastrointestinal hemorrhage

Objective To evaluate the preventive and therapeutic effects of cefotaxime sodium on nosocomial infection in patients with liver cirrhosis complicated with upper gastrointestinal bleeding.Methods From June 2017 to June 2018,80 patients with liver cirrhosis complicated with upper gastrointestinal bleeding were randomly divided into a control group(n=40) and a trial group(n=40),and all the patients in the control group were given the routine treatment,and the patients in the trial group were treated with cefotaxime sodium on the basis of the routine treatment.The incidences of infection,recurrent bleeding and death,and the changes of C-reactive protein(CRP) levels and white blood cell(WBC) counts were investigated and compared between the two groups,before and after the treatment.Results After the treatment,the CRP and WBC of the two groups improved,and the improvement of the trial group was superior to that of the control group.At the same time,the incidence of infection in the trial group(10.00%) was significantly lower than that in the control group(32.50%),and the incidences of recurrent bleeding and death were also lower than those in the control group(P <0.05).Conclusion The use of cefotaxime sodium in the prevention and treatment of nosocomial infection in patients with liver cirrhosis complicated with upper gastrointestinal hemorrhage can effectively reduce the infection,rebleeding and death,and alleviate the inflammatory reaction of the patients.